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Calcium Carbonate
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Flucillin
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Flucloxacillin
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Arendal
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Promiten
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Dextran
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Regaine for Men Gel
1. Name Of The Medicinal Product
Regaine for Men Gel
2. Qualitative And Quantitative Composition
Minoxidil 20 mg/g (2% w/w).
For excipients see section 6.1.
3. Pharmaceutical Form
Cutaneous Gel (to be applied to the scalp).
4. Clinical Particulars
4.1 Therapeutic Indications
Regaine for Men Gel is indicated for the treatment of alopecia androgenetica in men aged between 18 and 65.
Onset and degree of hair regrowth may be variable among users. Although trends in the data suggest that those users who are younger, who have been balding for a shorter period of time or who have a smaller area of baldness on the vertex are more likely to respond to Regaine for Men Gel, individual responses cannot be predicted.
4.2 Posology And Method Of Administration
Hair and scalp should be thoroughly dry prior to topical application of Regaine for Men Gel. A dose of 1 ml Regaine for Men Gel should be applied to the total affected areas of the scalp twice daily. The total daily dosage should not exceed 2 ml. If fingertips are used to facilitate drug application, hands should be washed afterwards.
It may take twice daily applications for four months or more before evidence of hair growth can be expected.
If hair regrowth occurs, twice daily applications of Regaine for Men Gel are necessary for continued hair growth. Anecdotal reports indicate that regrown hair may disappear three to four months after stopping Regaine for Men Gel application and the balding process will continue.
Users should discontinue treatment if there is no improvement after one year.
Children and the elderly
Not recommended. The safety and effectiveness of Regaine for Men Gel in users under 18 or over 65 years of age has not been established.
4.3 Contraindications
Regaine for Men Gel is contraindicated:
− in users with a history of sensitivity to minoxidil, ethanol, propylene glycol, carbomer and diisopropanolamine
− in users with treated or untreated hypertension
− in users with any scalp abnormality (including psoriasis and sunburn)
− in users with a shaved scalp
− if occlusive dressings or other topical medical preparations are being used.
4.4 Special Warnings And Precautions For Use
Before using Regaine for Men Gel, the user should determine that the scalp is normal and healthy.
The user should stop using Regaine for Men Gel and see a doctor if hypotension is detected or if the patient is experiencing chest pain, rapid heart beat, faintness or dizziness, sudden unexplained weight gain, swollen hands or feet or persistent redness.
Users with known cardiovascular disease or cardiac arrhythmia should contact a physician before using Regaine for Men Gel.
Regaine for Men Gel is for external use only. Do not apply to areas of the body other than the scalp.
Hands should be washed thoroughly after applying the gel.
Regaine for Men Gel contains an alcohol base which will cause burning and irritation of the eye. In the event of accidental contact with sensitive surfaces (eye, abraded skin and mucous membranes) the area should be bathed with large amounts of cool tap water.
Regaine for Men Gel contains propylene glycol, which may cause skin irritation.
Some users have experienced changes in hair colour and/or texture with use of Regaine for Men Gel.
Users should be advised to consult their doctor or pharmacist if they are concerned at any time during treatment with Regaine for Men Gel.
Users should be aware that, whilst extensive use of Regaine for Men Gel has not revealed evidence that sufficient minoxidil is absorbed to have systemic effects, greater absorption because of misuse, individual variability, unusual sensitivity or decreased integrity of the epidermal barrier caused by inflammation or disease processes in the skin (e.g. excoriations of the scalp, or scalp psoriasis) could lead, at least theoretically, to systemic effects.
4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction
Topical drugs, such as corticosteroids, tretinoin, dithranol or petrolatum which alter the stratum corneum barrier, could result in increased absorption of minoxidil if applied concurrently. Although it has not been clinically demonstrated, there exists the theoretical possibility of absorbed minoxidil potentiating orthostatic hypotension in patients concurrently taking peripheral vasodilators.
4.6 Pregnancy And Lactation
There is no evidence as to drug safety in human pregnancy nor is there evidence from animal work that it is free from hazard. Regaine for Men Gel should not be used during pregnancy or lactation.
4.7 Effects On Ability To Drive And Use Machines
Based on the pharmacodynamic and overall safety profile of minoxidil, it is not expected that Regaine for Men Gel would interfere with the ability to drive or operate machinery.
4.8 Undesirable Effects
In placebo controlled trials of Regaine, the overall frequency of medical events in females in all body system categories was approximately five times that of males.
Several thousand patients have used topical minoxidil in clinical trials where a comparison with an inactive solution was made. Dermatological reactions (e.g. irritation, itching) occurred in patients using both solutions. This has been explained by the presence of propylene glycol in both the active and inactive solution. Regaine for Men Gel also contains propylene glycol.
Reactions reported in commercial marketing experience include: hypertrichosis (unwanted non-scalp hair including facial hair growth in women), local erythema, itching, dry skin/scalp flaking, and exacerbation of hair loss. Users should stop using Regaine for Men Gel if they experience persistent redness or irritation of the scalp.
Some consumers reported increased hair shedding upon initiation of therapy with Regaine for Men Gel. This is most likely due to minoxidil's action of shifting hairs from the resting telogen phase to the growing anagen phase (old hairs fall out as new hairs grow in their place). This temporary increase in hair shedding generally occurs two to six weeks after beginning treatment and subsides within a couple of weeks. If shedding persists (>2 weeks), users should stop using Regaine for Men Gel and consult their doctor.
Particular attention has been paid to body systems, such as cardiovascular and metabolic, which might have some relevance based on the pharmacology of minoxidil. There was no increased risk to users due to drug related medical reactions in these, or other, body system categories.
Users should stop using Regaine for Men Gel if they experience chest-pain, tachycardia, faintness, dizziness, sudden unexplained weight gain, or swollen hands or feet. Rare cases of hypotension have been reported.
4.9 Overdose
Increased systemic absorption of minoxidil may potentially occur if higher-than-recommended doses of Regaine for Men Gel are applied to larger surface areas of the body or areas other than the scalp. There are no known cases of minoxidil overdosage resulting from topical administration of Regaine for Men Gel.
Because of the concentration of minoxidil in Regaine for Men Gel, accidental ingestion has the potential of producing systemic effects related to the pharmacological action of the drug (5 ml of Regaine for Men Gel contains 100 mg minoxidil, the maximum recommended adult dose for oral minoxidil administration in the treatment of hypertension). Signs and symptoms of minoxidil overdosage would most likely be cardiovascular effects associated with sodium and water retention and tachycardia. Fluid retention can be managed with appropriate diuretic therapy. Clinically significant tachycardia can be controlled by administration of a beta-adrenergic blocking agent.
5. Pharmacological Properties
5.1 Pharmacodynamic Properties
Minoxidil is a powerful vasodilator. It was noticed that in patients with severe hypertension, about 80% developed hypertrichosis as a side-effect.
Individual responses to Regaine are variable and unpredictable.
The effect of Regaine 2% solution has been assessed in phase III clinical trials in men conducted over a 48 week treatment period. In these studies Regaine 2% solution was compared to the product vehicle without the minoxidil active ingredient. The primary efficacy criterion was non-vellus hair count in a 1.0cm2 reference area of affected scalp. The mean changes observed in this parameter in these studies were significantly in favour of Regaine 2% solution and were as follows:
Mean change in non-vellus hair count in reference 1cm2 area of scalp compared with baseline
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In addition, efficacy was further assessed by comparing photographs taken at various timepoints with baseline. Assessment was undertaken by patients using a 100 mm visual analogue scale where point 0 represented much less scalp coverage, 50 mm no difference and 100 mm much more scalp coverage. The results were as follows:
Patient evaluation of change in scalp coverage
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Assessment was also undertaken by two blinded reviewers who compared photographs taken at baseline and after 48 weeks. Differences were assessed using a 7 point categorical scale viz:
Dense growth
Moderate growth
Minimal Growth
No change
Minimal loss
Moderate loss
Dense loss
The results were as follows:
Photographic Evaluation of Clinical Response (Reviewer 1)
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Photographic Evaluation of Clinical Response (Reviewer 2)
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Based upon the photographic data around 40% of the patients experienced an increased scalp coverage after 48 weeks treatment with Regaine 2% solution as defined by regrowth of hair compared with 23% at an average for those who received vehicle alone. Around 19% treated with Regaine 2% solution experienced dense or moderate regrowth compared with around 7% who received vehicle alone. In addition 49% of patients who received Regaine 2% solution were adjudged to have no change between the photographic assessments of hair growth compared with 60% who received vehicle alone. Stabilisation of hair loss (i.e. regrowth or no loss) can therefore be expected in about 4 out of 5 patients using Regaine 2% solution compared with 3 out of 4 patients using vehicle alone.
The mechanism by which minoxidil stimulates hair growth is not fully understood, but minoxidil can reverse the hair loss process of androgenetic alopecia by the following means:
- increasing the diameter of the hair shaft
- stimulating anagen growth
- prolonging the anagen phase
- stimulating anagen recovery from the telogen phase
As a peripheral vasodilator minoxidil enhances microcirculation to hair follicles. The Vascular Endothelial Growth Factor (VEGF) is stimulated by minoxidil and VEGF is presumably responsible for the increased capillary fenestration, indicative of a high metabolic activity, observed during the anagen phase.
5.2 Pharmacokinetic Properties
The failure to detect evidence of systemic effects during treatment with Regaine 2% solution reflects the poor absorption of topical minoxidil, which averages about 1.4% (range 0.3-4.5%) of the total applied dose from normal intact skin. Absorption is about 2% when applied topically to shaved scalps of hypertensive users.
Results of extensive pharmacokinetic studies indicate that the three major factors by which topical minoxidil absorption is increased are: increasing the dose applied, increasing the frequency of dosing and decreasing the barrier function of the stratum corneum.
Serum minoxidil levels and systemic effects resulting from administration of Regaine are governed by the drug's absorption rate through the skin. Following cessation of topical dosing, approximately 95% of the systemically absorbed drug is eliminated within 4 days. Minoxidil and its metabolites are excreted principally in the urine.
5.3 Preclinical Safety Data
Preclinical data reveal no special hazards for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity or carcinogenic potential.
Cardiac effects of minoxidil in dogs are species-specific in terms of the low doses that cause profound haemodynamic effects and associated changes in the heart. Available data indicate that similar cardiac effects do not occur in humans treated topically or orally with minoxidil.
In rat fertility studies, minoxidil at dose levels between 3 and 80 mg/kg exhibited adverse effects on fertility. Animal reproduction toxicity studies have shown a risk to the foetus at exposure levels that in comparison to levels obtained in humans are very high (doses that ranged from 569- to 1139-fold anticipated human exposures) and showed signs of maternal toxicity.
6. Pharmaceutical Particulars
6.1 List Of Excipients
Propylene glycol
Ethanol
Carbomer
Diisopropanolamine
Water
6.2 Incompatibilities
None known.
6.3 Shelf Life
24 months
6.4 Special Precautions For Storage
Do not store above 25˚C. Regaine for Men Gel is flammable.
6.5 Nature And Contents Of Container
Polyethylene bottle containing 60 ml of gel. An integral metered pump is included.
6.6 Special Precautions For Disposal And Other Handling
One press of the integral pump supplies 0.5 ml of gel. Regaine for Men Gel is flammable. Do not use while smoking, or near any naked flame or strong heat source. Avoid exposure of the container and contents to naked flames during use, storage and disposal.
Administrative Data
7. Marketing Authorisation Holder
McNeil Products Limited
Foundation Park
Roxborough Way
Maidenhead
Berkshire SL6 3UG
United Kingdom
8. Marketing Authorisation Number(S)
PL 15513/0129
9. Date Of First Authorisation/Renewal Of The Authorisation
9 June 2005
10. Date Of Revision Of The Text
11th April 2008
Rompirin
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Cimetidine
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Artesunate
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Methylthioninium Chloride
In some countries, this medicine may only be approved for veterinary use.
Scheme
Rec.INN
ATC (Anatomical Therapeutic Chemical Classification)
V03AB17,V04CG05
CAS registry number (Chemical Abstracts Service)
0000061-73-4
Chemical Formula
C16-H18-Cl-N3-S
Molecular Weight
319
Therapeutic Categories
Diagnostic agent
Urinary tract antiseptic
Antidote in methemoglobinemia
Chemical Name
Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride
Foreign Names
- Methylthioninii Chloridum (Latin)
- Methylthioninium chlorid (German)
- Chlorure de Méthylthioninium (French)
- Cloruro de metiltioninio (Spanish)
Generic Names
- Bleu de méthylène (OS: DCF)
- Methylene Blue (OS: BAN)
- Methylthioninium Chloride (OS: BAN)
- Metiltioninio clorure (OS: DCIT)
- Methylenblau (IS)
- Methylenum coeruleum (IS)
- Tetramethylthioninium chloratum (IS)
- Methylene Blue (PH: USP 32)
- Methylthionini chloridum (PH: Ph. Int. 2)
- Methylthioninii chloridum (PH: Ph. Int. 4, Ph. Eur. 6)
- Methylthioninium Chloride (PH: Ph. Eur. 6, BP 2010)
- Methylthioniniumchlorid (PH: Ph. Eur. 6)
Brand Names
- Azul de Metileno
Valma, Chile; Volta, Chile - Centilux (Methylthioninium Chloride and Naphazoline)
Alcon, Spain - Collyre Bleu Laiter (Methylthioninium Chloride and Naphazoline)
Leurquin, France; Uhlmann-Eyraud Pharma, Switzerland - Methylene Blue for Injection DBL
AFT, New Zealand - Methylene Blue Injection USP
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IFET, Greece; MaCarthys, Malta - Methylthioninum Chloride (veterinary use)
Martindale Animalhealth, United Kingdom - Metiltioninio Cloruro Afom
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Star, United States
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Glossary
| BAN | British Approved Name |
| DCF | Dénomination Commune Française |
| DCIT | Denominazione Comune Italiana |
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| OS | Official Synonym |
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| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
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Isosorbide Mononitrate
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Tranexamic Acid
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| DCIT | Denominazione Comune Italiana |
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Benzylhydrochlorothiazide
Scheme
JAN
CAS registry number (Chemical Abstracts Service)
0001824-50-6
Chemical Formula
C14-H14-Cl-N3-O4-S2
Molecular Weight
387
Therapeutic Categories
Diuretic agent
Antihypertensive agent
Chemical Name
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(phenylmethyl)-, 1,1-dioxide
Foreign Name
- Benzylhydrochlorothiazid (German)
Generic Name
- Benzylhydrochlorothiazide (OS: JAN)
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- Behyd RA (Benzylhydrochlorothiazide and Reserpine)
Kyorin, Japan - Behyd
Kyorin, Japan; Shinlin Sinseng, Taiwan - Tenazide (Benzylhydrochlorothiazide and Enalapril)
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Geneprami
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Albalon
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Naphazoline
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C. M.P.200
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Ranitidine
Ranitidine hydrochloride (a derivative of Ranitidine) is reported as an ingredient of Ratinal in the following countries:
- Indonesia
International Drug Name Search
Rephoren
Rephoren may be available in the countries listed below.
Ingredient matches for Rephoren
Calcium Acetate
Calcium Acetate is reported as an ingredient of Rephoren in the following countries:
- United Kingdom
Magnesium Carbonate
Magnesium Carbonate heavy (a derivative of Magnesium Carbonate) is reported as an ingredient of Rephoren in the following countries:
- United Kingdom
International Drug Name Search
Clopidogrel AAA
Clopidogrel AAA may be available in the countries listed below.
Ingredient matches for Clopidogrel AAA
Clopidogrel
Clopidogrel is reported as an ingredient of Clopidogrel AAA in the following countries:
- Germany
International Drug Name Search
Folsäure-Hevert
Folsäure-Hevert may be available in the countries listed below.
Ingredient matches for Folsäure-Hevert
Folic Acid
Folic Acid is reported as an ingredient of Folsäure-Hevert in the following countries:
- Germany
International Drug Name Search
Monday, October 17, 2016
Povidine
In the US, Povidine is a member of the following drug classes: antiseptic and germicides, vaginal anti-infectives.
Ingredient matches for Povidine
Povidone Iodine
Povidone-Iodine is reported as an ingredient of Povidine in the following countries:
- Bangladesh
- India
- Venezuela
International Drug Name Search
Sunday, October 16, 2016
Ferro Gyn
Ferro Gyn may be available in the countries listed below.
Ingredient matches for Ferro Gyn
Ferrous Glycine Sulfate
Ferrous Glycine Sulfate is reported as an ingredient of Ferro Gyn in the following countries:
- Peru
Folic Acid
Folic Acid is reported as an ingredient of Ferro Gyn in the following countries:
- Peru
International Drug Name Search
Cefazolina Germed
Cefazolina Germed may be available in the countries listed below.
Ingredient matches for Cefazolina Germed
Cefazolin
Cefazolin sodium salt (a derivative of Cefazolin) is reported as an ingredient of Cefazolina Germed in the following countries:
- Italy
International Drug Name Search
Tyklid
Tyklid may be available in the countries listed below.
Ingredient matches for Tyklid
Ticlopidine
Ticlopidine hydrochloride (a derivative of Ticlopidine) is reported as an ingredient of Tyklid in the following countries:
- India
International Drug Name Search
Saturday, October 15, 2016
KLEAN PREP 69g, sachet powder for oral solution
1. Name Of The Medicinal Product
KLEAN-PREP 69g, sachet powders for oral solution.
2. Qualitative And Quantitative Composition
Each sachet of KLEAN-PREP contains the following active ingredients:
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The content of electrolyte ions per sachet when made up to one litre of water is as follows:
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For excipients, see 6.1.
3. Pharmaceutical Form
A whitish powder which, when dissolved in water, gives a clear, colourless solution for oral administration.
4. Clinical Particulars
4.1 Therapeutic Indications
For colonic lavage prior to diagnostic examination or surgical procedures requiring a clean colon, e.g. colonoscopy, barium enema or colonic resection.
4.2 Posology And Method Of Administration
Adults: Each sachet should be dissolved in 1 litre of water. The usual dose is up to 4 sachets taken at a rate of 250 ml every 10 to 15 minutes until the total volume is consumed or rectal effluent is clear, or as directed by the physician.
The solutions from all 4 sachets should be drunk within 4 to 6 hours. Alternatively, administration may be divided, for example, taking 2 sachets during the evening before the examination, and the remaining 2 sachets on the morning of the examination.
If administration is by nasogastric tube, the usual rate should be 20 to 30 ml/minute.
Children: There is no recommended dosage.
Renal patients: No dosage adjustment need be made.
4.3 Contraindications
Use in patients with known or suspected gastrointestinal obstruction or perforation, ileus, gastric retention, toxic colitis and toxic megacolon.
Congestive cardiac failure (NYHA class III and IV)
Hypersensitivity to any of the ingredients.
4.4 Special Warnings And Precautions For Use
No solid food should be eaten for at least 2 hours before taking KLEAN-PREP. The product should only be administered with caution to patients with impaired gag reflex, reflux oesophagitis, or those with diminished levels of consciousness and patients with ulcerative colitis.
Unconscious, semi-conscious patients or patients prone to aspiration or regurgitation should be observed during administration especially if this is via the nasogastric route. There have been reports of pulmonary oedema resulting from aspiration of macrogol lavage solutions requiring immediate treatment.
Although not expected due to the isotonic composition of the product, cases of electrolyte disturbances have been rarely reported in at-risk patients. Therefore, KLEAN-PREP should be used with care in patients at risk of electrolyte disturbance, such as patients with renal failure, mild (NYHA class I and II) congestive cardiac impairment (see also section 4.3), or those simultaneously treated with diuretics.
Should abdominal distension or pain arise, the rate of administration should be slowed down or temporarily stopped until symptoms subside.
KLEAN-PREP contains aspartame, which is metabolised to phenylalanine. This may be harmful for patients with phenylketonuria.
Caution should be used in the administration of KLEAN-PREP to elderly, fragile or debilitated patients.
4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction
Oral medication taken within one hour of administration of KLEAN-PREP may be flushed from the gastro-intestinal tract and not absorbed.
4.6 Pregnancy And Lactation
The preparation should only be used during pregnancy and lactation if considered essential by the physician. There is no experience of use during pregnancy. The purpose and mechanisms of use should be borne in mind if the physician is considering administration.
4.7 Effects On Ability To Drive And Use Machines
There is no known effect on the ability to drive and use machines.
4.8 Undesirable Effects
The most commonly experienced undesirable effects are gastrointestinal in nature. The following Adverse Events have been observed in post-marketing experience and therefore the frequencies are not known:
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Transient increases in blood pressure have been observed in association with bowel preparations.
4.9 Overdose
In case of gross accidental overdosage, where diarrhoea is severe, conservative measures are usually sufficient; generous amounts of fluid, especially fruit juices, should be given.
5. Pharmacological Properties
5.1 Pharmacodynamic Properties
ATC Code: A06A D
Macrogol 3350 exerts its effects by virtue of its osmotic effect in the gut, which induces a laxative effect. Electrolytes are present in the formulation and are exchanged across the intestinal barrier (mucosa) with serum electrolytes and water to prevent the occurrence of potential clinically significant variations of net electrolyte or net water balance.
Macrogol 3350 increases the stool volume, which triggers colon motility via neuromuscular pathways. The physiological consequence is an improved propulsive colonic transportation of the softened stools and a facilitation of the defecation.
5.2 Pharmacokinetic Properties
Macrogol 3350 is unchanged along the gut. It is virtually unabsorbed from the gastro-intestinal tract. Any macrogol 3350 that is absorbed is excreted via the urine.
5.3 Preclinical Safety Data
Preclinical studies provide evidence that macrogol 3350 has no significant systemic toxicity potential.
6. Pharmaceutical Particulars
6.1 List Of Excipients
Vanilla flavour
Aspartame.
6.2 Incompatibilities
None are known.
6.3 Shelf Life
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6.4 Special Precautions For Storage
Sachets: Store in a dry place. Do not store above 25°C.
Reconstituted solution: Store in a refrigerator (2 – 8°C)
6.5 Nature And Contents Of Container
Sachets containing 69gm white powder, in a box of 4 sachets.
6.6 Special Precautions For Disposal And Other Handling
The solution should be used within 24 hours.
ADMINISTRATIVE DATA
7. Marketing Authorisation Holder
Norgine Limited
Norgine House
Widewater Place
Moorhall Road
Harefield
UXBRIDGE
Middlesex UB9 6NS
United Kingdom.
8. Marketing Authorisation Number(S)
PL: 00322/0068.
9. Date Of First Authorisation/Renewal Of The Authorisation
August 1991/March 1997.
10. Date Of Revision Of The Text
Feb 2011
Bupivacaina Angelini
Bupivacaina Angelini may be available in the countries listed below.
Ingredient matches for Bupivacaina Angelini
Bupivacaine
Bupivacaine hydrochloride (a derivative of Bupivacaine) is reported as an ingredient of Bupivacaina Angelini in the following countries:
- Italy
International Drug Name Search
Maveral
Maveral may be available in the countries listed below.
Ingredient matches for Maveral
Fluvoxamine
Fluvoxamine maleate (a derivative of Fluvoxamine) is reported as an ingredient of Maveral in the following countries:
- Italy
International Drug Name Search
Lansoprazol KRKA
Lansoprazol KRKA may be available in the countries listed below.
Ingredient matches for Lansoprazol KRKA
Lansoprazole
Lansoprazole is reported as an ingredient of Lansoprazol KRKA in the following countries:
- Denmark
- Finland
- Norway
- Sweden
International Drug Name Search
Pantosec-D
Pantosec-D may be available in the countries listed below.
Ingredient matches for Pantosec-D
Domperidone
Domperidone is reported as an ingredient of Pantosec-D in the following countries:
- India
Pantoprazole
Pantoprazole is reported as an ingredient of Pantosec-D in the following countries:
- India
International Drug Name Search
Friday, October 14, 2016
Colistin Link
Colistin Link may be available in the countries listed below.
Ingredient matches for Colistin Link
Colistin Sulfate
Colistin sulphomethate sodium (a derivative of Colistin) is reported as an ingredient of Colistin Link in the following countries:
- Australia
- New Zealand
International Drug Name Search
Ximocef
Ximocef may be available in the countries listed below.
Ingredient matches for Ximocef
Cefpodoxime
Cefpodoxime is reported as an ingredient of Ximocef in the following countries:
- Bangladesh
International Drug Name Search
Cardigard
Cardigard may be available in the countries listed below.
Ingredient matches for Cardigard
Carvedilol
Carvedilol is reported as an ingredient of Cardigard in the following countries:
- Bangladesh
International Drug Name Search
Thursday, October 13, 2016
Lecimar
Lecimar may be available in the countries listed below.
Ingredient matches for Lecimar
Fluoxetine
Fluoxetine hydrochloride (a derivative of Fluoxetine) is reported as an ingredient of Lecimar in the following countries:
- Spain
International Drug Name Search
Paclitaxel-Teva
Paclitaxel-Teva may be available in the countries listed below.
Ingredient matches for Paclitaxel-Teva
Paclitaxel
Paclitaxel is reported as an ingredient of Paclitaxel-Teva in the following countries:
- Czech Republic
- Estonia
- France
- Hungary
- Italy
- Latvia
- Lithuania
- Slovakia
- Spain
- Sweden
- Switzerland
International Drug Name Search
Feedmix TS
Feedmix TS may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Ingredient matches for Feedmix TS
Sulfamethoxazole
Sulfamethoxazole is reported as an ingredient of Feedmix TS in the following countries:
- Netherlands
Trimethoprim
Trimethoprim is reported as an ingredient of Feedmix TS in the following countries:
- Netherlands
International Drug Name Search
Gizende
Gizende may be available in the countries listed below.
Ingredient matches for Gizende
Heparin
Heparin sodium salt (a derivative of Heparin) is reported as an ingredient of Gizende in the following countries:
- Georgia
International Drug Name Search
Wednesday, October 12, 2016
Ketoprofen SR
Ketoprofen SR may be available in the countries listed below.
Ingredient matches for Ketoprofen SR
Ketoprofen
Ketoprofen is reported as an ingredient of Ketoprofen SR in the following countries:
- Romania
International Drug Name Search
Bassamin
Bassamin may be available in the countries listed below.
Ingredient matches for Bassamin
Aspirin
Acetylsalicylic Acid is reported as an ingredient of Bassamin in the following countries:
- Japan
International Drug Name Search
Clinax
Clinax may be available in the countries listed below.
Ingredient matches for Clinax
Minocycline
Minocycline is reported as an ingredient of Clinax in the following countries:
- Argentina
Sulindac
Sulindac is reported as an ingredient of Clinax in the following countries:
- Japan
International Drug Name Search
Flagyl Vaginal
Flagyl Vaginal may be available in the countries listed below.
Ingredient matches for Flagyl Vaginal
Metronidazole
Metronidazole is reported as an ingredient of Flagyl Vaginal in the following countries:
- Spain
International Drug Name Search
Tuesday, October 11, 2016
Halfdopa
Halfdopa may be available in the countries listed below.
Ingredient matches for Halfdopa
Methyldopa
Methyldopa is reported as an ingredient of Halfdopa in the following countries:
- Japan
International Drug Name Search
Balsoclase
Balsoclase may be available in the countries listed below.
Ingredient matches for Balsoclase
Carbocisteine
Carbocisteine is reported as an ingredient of Balsoclase in the following countries:
- Belgium
Pentoxyverine
Pentoxyverine citrate (a derivative of Pentoxyverine) is reported as an ingredient of Balsoclase in the following countries:
- Belgium
- Luxembourg
- Netherlands
International Drug Name Search
Letrozole
In the US, Letrozole (letrozole systemic) is a member of the following drug classes: aromatase inhibitors, hormones/antineoplastics and is used to treat Breast Cancer, Breast Cancer - Adjuvant, Breast Cancer - Metastatic and Female Infertility.
US matches:
- Letrozole
Scheme
Rec.INN
ATC (Anatomical Therapeutic Chemical Classification)
L02BG04
CAS registry number (Chemical Abstracts Service)
0112809-51-5
Chemical Formula
C17-H11-N5
Molecular Weight
285
Therapeutic Categories
Antineoplastic agent
Enzyme inhibitor, aromatase
Chemical Name
Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-
Foreign Names
- Letrozolum (Latin)
- Letrozol (German)
- Letrozole (French)
- Letrozol (Spanish)
Generic Names
- Letrozole (OS: USAN, BAN)
- CGS 20267 (IS: Ciba-Geigy)
- Letrozole (PH: USP 32, Ph. Eur. 5, BP 2010)
- Letrozolum (PH: Ph. Eur. 6)
Brand Names
- Aromek
Celon, Poland - Cendalon
Teva, Argentina - Etruzil
Egis, Slovakia - Fecinole
Dosa, Argentina; Medigroup, Peru - Femaplex
Genepharm, Greece - Femar
Novartis, Denmark; Novartis, Finland; Novartis, Iceland; Novartis, Norway; Novartis, Sweden - Femara
Delphi, Netherlands; Euro, Netherlands; Novartis, United Arab Emirates; Novartis, Argentina; Novartis, Austria; Novartis, Australia; Novartis, Bosnia & Herzegowina; Novartis, Bangladesh; Novartis, Belgium; Novartis, Bulgaria; Novartis, Bahrain; Novartis, Brazil; Novartis, Canada; Novartis, Switzerland; Novartis, Chile; Novartis, China; Novartis, Colombia; Novartis, Czech Republic; Novartis, Germany; Novartis, Ecuador; Novartis, Estonia; Novartis, Egypt; Novartis, Spain; Novartis, United Kingdom; Novartis, Greece; Novartis, Hong Kong; Novartis, Croatia (Hrvatska); Novartis, Hungary; Novartis, Indonesia; Novartis, Ireland; Novartis, Israel; Novartis, Iraq; Novartis, Iran; Novartis, Italy; Novartis, Jordan; Novartis, Japan; Novartis, Kuwait; Novartis, Lebanon; Novartis, Sri Lanka; Novartis, Lithuania; Novartis, Luxembourg; Novartis, Latvia; Novartis, Malta; Novartis, Mexico; Novartis, Malaysia; Novartis, Netherlands; Novartis, New Zealand; Novartis, Oman; Novartis, Philippines; Novartis, Poland; Novartis, Portugal; Novartis, Qatar; Novartis, Romania; Novartis, Serbia; Novartis, Russian Federation; Novartis, Saudi Arabia; Novartis, Singapore; Novartis, Slovenia; Novartis, Slovakia; Novartis, Syria; Novartis, Thailand; Novartis, Turkey; Novartis, Taiwan; Novartis, United States; Novartis, Venezuela; Novartis, Vietnam; Novartis, Yemen; Novartis, South Africa; Novartis Pharmaceuticals, Peru - Fémara
Novartis, France; Novartis, France; Novartis, Tunisia; Novartis, Tunisia - Femtozone
Helm, Slovakia - Kebirzol
Aspen, Argentina - Lametta
Vipharm, Poland - Leoncol
Pharmanel, Greece - Letrol
Renata, Bangladesh - Letropen
Elpen, Greece - Letroz
Sun, Myanmar - Letrozin
Meditrina, Greece - Letrozol Microsules
Microsules, Argentina - Letrozol Nucleus
Rottendorf, Bulgaria; Synthon, Bulgaria; Synthon, Bulgaria - Letrozol Sandoz
Lek, Bulgaria; Rottendorf, Bulgaria; Sandoz, Slovakia; Synthon, Bulgaria - Letrozol Streuli
Streuli Pharma, Switzerland - Letrozol Teva
Teva, Slovakia - Letrozole Helm
Medihelm, Greece - Letrozole Medico Uno
Medico Uno, Slovakia - Letrozol-Mepha
Mepha Pharma, Switzerland - Letrozolum Genthon
Genthon, Slovakia - Letrozolum Polpharma
Polpharma, Slovakia - Letrozolum Synthon
Synthon, Slovakia - Levinox
Santa, Greece - Linol
Vianex / BIANEΞ, Greece - Loosyn
Synthon, Slovakia - Losiral
Farmindustria, Peru; Neoraxis, Chile; Recalcine, Ecuador - Loxifan
Padro, Spain - Mimor
png Gerolymatos, Greece - Picozone
Helm, Slovakia - Trozet
Dabur, India
International Drug Name Search
Glossary
| BAN | British Approved Name |
| IS | Inofficial Synonym |
| OS | Official Synonym |
| PH | Pharmacopoeia Name |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
| USAN | United States Adopted Name |
Click for further information on drug naming conventions and International Nonproprietary Names.
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